KetoCal 4:1 (US)

A nutritionally complete, ketogenic formula in a 4:1 ratio (fat:carbohydrate+ protein) for the dietary management of intractable epilepsy; designed for individuals over the age of one year. A medical food. Click here to visit the KetoCal website.

• KetoCal 4:1 and KetoCal 3:1 can be ordered directly from Nutricia directly by calling 1-866-KETOCAL (538-6225). In order to purchase KetoCal, your healthcare provider must complete a Consent Form. For more information, click here.

This formulation is only available in the US.

Directions for Preparation and Use:

• Intake to be determined by a medical professional and is dependent on the age, body weight and medical condition of the patient.

For oral or tube feeding:

• Measure the required amount of warm water into a container that seals with a screw top lid. To completely dissolve the powder, the water must be at a temperature of 113-122°F.
• Add the prescribed amount of KetoCal to the water.
• Cover and shake until the powder has dissolved.
• Once prepared, the formula should be stored in a refrigerator and kept no longer than 24 hours. KetoCal can be kept at room temperature for a maximum of 4 hours.
• Shake or stir immediately before serving. For oral feeding, KetoCal is best served chilled.

To obtain the recommended dilution of 4 mL of water to 1 g of powder, mix the following amounts of water and powder:

Precaution:
Use only under strict medical supervision. Not for parenteral use. Not suitable for children under one year of age.

Storage:

• Store unopened can at room temperature. Once opened, reseal can and store in a cool, dry place (not in a refrigerator) and use within one month.

KetoCal 4:1 and KetoCal 3:1 can be ordered directly from Nutricia directly by calling 1-866-KETOCAL (538-6225). In order to purchase KetoCal, your healthcare provider must complete a Consent Form. For more information, click here.

Clinical References

1. Coppola G, Verrotti A, Ammendola E, Operto FF, Corte RD, Signoriello G, Pascotto A. Ketogenic diet for the treatment of catastrophic epileptic encephalopathies in childhood. Eur J Paediatr Neurol. 2009 Jul 24. [Epub ahead of print]

Clinical References for the Ketogenic Diet

1. Neal EG, Chaffe H, Schwartz RH, Lawson MS, Edwards N, Fitzsimmons G, Whitney A, Cross JH. The ketogenic diet for the treatment of childhood epilepsy: a  randomised controlled trial.  Lancet Neurol. 2008 Jun;7(6):500-6.
2. Zupec-Kania BA, Spellman E. An overview of the ketogenic diet for pediatric epilepsy. Nutr Clin Pract. 2008 Dec-2009 Jan;23(6):589-96.
3. Henderson CB, Filloux FM, Alder SC, Lyon JL, Caplin DA. Efficacy of the ketogenic diet as a treatment option for epilepsy: meta-analysis. J Child Neurol. 2006 Mar;21(3):193-8.